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Mythili Markowski, Ph.D.

Mythili Markowski, Ph.D.


Alexandria, VA

How Mythili Helps Clients

Dr. Markowski focuses her practice on intellectual property law, where she has been associated with a number of inter partes review and patent interference matters before the Patent Trial and Appeal Board on behalf of Petitioners and Patent Owners. A number of these inter partes review proceedings were co-pending with district court action. Mythili’s inter partes review experience includes involvement in all phases of the review proceedings.

In 2018 and 2020, Mythili was named one of Managing Intellectual Property's IP Stars. 

Mythili’s IP district court litigation experience includes a special emphasis on pharmaceutical patent litigation under the Hatch-Waxman Act. Mythili has extensive pre-filing counseling experience that includes evaluating innovator IP portfolios from a generic perspective. She has drafted hundreds of invalidity, non-infringement and freedom-to-operate opinions related to small molecule therapeutic compounds, pharmaceutical formulations, crystalline polymorphs, enantiomers, solvates, salts, dosage forms (including oral, topical, ophthalmic, nasal and parenteral dosage forms), pharmacokinetics, pharmacodynamics, biologics, methods of production and methods of use/treatment. Whether it is a question of certification filing strategy, the possibility of designing around an innovator’s product, the impact of a use code or data exclusivity or patent term extension, Mythili is able to assist her clients with assessing all pre-filing options. Her post-filing experience includes all aspects of Hatch-Waxman district court litigation, from answering a complaint to drafting invalidity and non-infringement contentions, motion briefs, summary judgment briefs and statements of material facts, to discovery, to settlement. She has extensive experience in the recruitment, management and deposition of litigation experts.

Mythili also maintains an IP counseling practice, which incorporates IP procurement, IP due diligence, as well as preparing all types of IP opinions, including patentability, freedom-to-operate, invalidity and non-infringement opinions. She has experience in tailoring IP protection plans for clients who balance trade secrets with patent portfolios.

Mythili’s graduate research was primarily focused on determining the three-dimensional structure of a protein involved in axon guidance, MICAL (Molecule Interacting with Cas-L). After obtaining structural data pertaining to this protein, she was able to establish spectrophotometric assays to monitor MICAL's catalytic activity. The protein studied is critical for proper nerve path-finding in the embryonic and adult nervous systems. Her technical knowledge also includes molecular biology, protein biochemistry, powder X-ray crystallography, enzymology, neuroscience, biotechnology, nanotechnology, immunology and cell biology.

How Mythili Helps Clients

Mythili strives to assist her clients with identifying the most advantageous intellectual property avenues to pursue. She works with clients to develop patent portfolios that avoid or overcome the intellectual property of competitors. She also works diligently with small inventor clients to keep patent prosecutions costs low.

Outside the Office

During her free time, Mythili likes to ride her Suzuki GZ250, bake and chauffeur her three kids to various weekend activities.